While on Dancing With The Stars, Anne Heche stated that, after attending the Opening of the movie Volcano, with Ellen DeGeneres in-hand, her career really suffered. She said, "It was painfully obvious that the Studio didn't like me showing up with a famous lesbian." Shoot, before seeing that segment of DWTS, neither wife nor I knew Anne was a lesbian. And, my wife was an "Extra" in that movie.
Studios are concerned with Optics. I think some people go to the movies to see the stars that are in it, story itself is immaterial.
Hollywood discriminates every hour of every day...but against gays???? She's blaming her lack of success on an attribute that should work to her benefit in her chosen profession. To paraphrase @Beth Gallagher ..."Anne WHO???"