May have found it. After a lifetime of pretty clean living, my kidneys have quit, rather quickly. After numerous doctors, 2 hospitals, specialists, the diagnosis finally made, after kidney biopsy, is MINIMAL CHANGE DISEASE. https://www.kidney.org/atoz/content/minimal-change-disease The cause? ASPARTAME! In an 11-year study by scientists at the Brigham and Women’s Hospital in Boston, there was a strong positive correlation found between degeneration of kidney function and consumption of aspartame-containing diet soda. Published in the Clinical Journal of the American Society of Nephrology, the study followed 3,318 women for a number of years as they consumed diet soda containing artificial sweeteners like Aspartame. Scientists took into account each participant’s age, blood pressure, smoking habits (when applicable), and pre-existing conditions like heart disease or diabetes, and administered food frequency questionnaires in 1984, 1986, 1990, 1994, and 1998. Two or more diet drinks daily, it was found, led to a doubled risk in fast-paced kidney decline. https://naturalsociety.com/aspartame-alert-diet-soda-destroys-kidney-function/ It was highly contested when introduced. Decisions reached highest levels of Washington. Tons of money were involved. The Director, FDA, refused approval for universal sweetener use. Secretary of State Donald Rumsfeld engaged to have him replaced by a "yes-man". He approved. Why? He sat on the Board of Directors of G.D. Searle, the company holding the patents. Much controversy, many "scientific" studies conducted, no real solid accepted conclusions, but today, after enjoying sweetness without sugar, my kidneys are dead! SUGAR never hurt!