The sweetener that your grandmother used back then would have been saccharin, which has been in use since at least before the Second World War, because I remember people talking about using it when they could not get sugar due to food rationing. Although it has been said to be bad for you, as far as I know it has never produced seizures, or any of the other side effects that can come from aspartame, and it is still on the market. Splenda, although not supposed to be good for you either, is also different from aspartame, which is the sweetener that @Frank Sanoica is talking about. And I don't think that Frank was trying to deny that people die from alcoholism, either; but he was trying to point out that you can die from wood alcohol, because it is not safe to drink in ANY quantities. A few sips of grain alcohol is not likely to kill a person outright like the same amount of wood alcohol would do.